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Bank of Japan: The index of small non-manufacturers rose for the second consecutive quarter, reaching the highest level since August 1991.Futures on the Nikkei Stock Exchange of Singapore opened down 175 points to 39,635.Onlikon: The cooperative product Aidit calcitonin soft capsules is planned to be selected for the tenth batch of national centralized drug procurement. Onlikon announced on December 13th, and on December 12th, the company received a notice from its partner Beijing Meifurun Pharmaceutical Technology Co., Ltd. (hereinafter referred to as "Meifurun") that the Aidit calcitonin soft capsules jointly developed by the company and its wholly-owned subsidiary Wenzhou Haihe Pharmaceutical Co., Ltd. are planned to be selected for the tenth batch of national centralized drug procurement. According to the Pharmaceutical Cooperation Agreement signed by the company and its partner Mei Furun, the company owns 50% of the cooperative products.

Apple is reported to cooperate with Broadcom to develop AI chips, and TSMC's advanced process will welcome big orders again. On December 13, it was reported that Apple intends to invest in self-developed AI chips, jointly develop them with Broadcom, and produce them in TSMC's 3 nm process, and mass-produce them in 2026. The legal person is optimistic that after the development of Apple's self-developed AI chip is completed, the investment is expected, and TSMC's advanced process will usher in another big order. It is understood that Apple's current A-series processors for iPhone and M-series processors for Mac all adopt self-developed strategies, and are exclusively manufactured by TSMC. The legal person believes that once Apple's self-developed chips are extended to AI chips, the cooperation with TSMC will be closer. (Taiwan Province Economic Daily)"Shanghai housing subsidy is 300,000 yuan" and "down payment is 20,000 yuan to buy 1.8 million hardcover existing houses"? Rumor has come. Recently, there have been a number of housing advertisements on the short video platform. The agent who released the housing claimed that he could receive the "housing subsidy" when buying a house in Shanghai, with the amount ranging from 200,000 yuan to 300,000 yuan. An intermediary declared: "Shanghai Songjiang New Town has a total price of 760,000 yuan and a housing subsidy of 250,000 yuan." "After receiving the subsidy, you can buy a 78-square-meter house with a down payment of 50,000 yuan." There is also an intermediary who claims: "The minimum payment can be only 20,000 yuan, and you can buy a finely decorated existing house with a total price of 1.8 million yuan." The reporter consulted a number of intermediaries and learned that the so-called "purchase subsidies" appearing in short videos are not government subsidies, but gimmicks. When the house-watchers consult subsidies on the spot, different intermediaries will have different calibers. Usually, there are three routines-one is to raise the price first and then lower the price. Second, the so-called "subsidy" is actually that developers lend money to buyers to pay down payment, and buyers have to pay interest. Third, the commission returned by the intermediary to the buyers is packaged as a "subsidy". (Shanghai rumor platform)Japanese and Korean stock markets opened lower, with the Nikkei 225 index down 0.56% at 39,624.05. South Korea's KOSPI index opened down 0.3% to 2,473.75 points.

Ministry of Finance of Korea: If the volatility is excessively intensified, more market stabilization measures will be taken.After the short-term survey was released, the 10-year Japanese government bond futures rose to 142.51.Citic Jiantou Pharmaceutical's 2025 strategy: looking for new additions and integration opportunities. Citic Jiantou said that looking forward to 2025, the reform policy in the medical field has been normalized, and the most noteworthy incremental policy in the medical insurance field is to establish a diversified payment system. The medical field is about to usher in the reform of "deep water areas" such as salary system and graded diagnosis and treatment, which is in line with expectations as a whole. At the same time, the innovation of China's pharmaceutical industry has gradually stepped onto the international stage, some sub-sectors will be marginally improved, and industry integration will begin. We are optimistic about the investment opportunities in the pharmaceutical industry in 2025. It is suggested to focus on the new increase (innovation, going out to sea, marginal change) and industry integration opportunities.